Macroape is an abbreviation for MAtrix CompaRisOn by Approximate P-value Estimation. It's a bioinformatic tool for evaluating similarity measure and best alignment between a pair of Position Weight Matrices(PWM), finding thresholds by P-values and vice versa and even searching a collection of motifs for the most similar ones. Used approach and application described in manual at https://docs.google.com/document/pub?id=1_jsxhMNzMzy4d2d_byAd3n6Szg5gEcqG_Sf7w9tEqWw